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A 53-year-old female asked:

Sle pt. sed rate >140 but crp normal. dr says i have pleuritis but sed has never been this high. trying to understand. ?

1 doctor answer4 doctors weighed in
Dr. John Chiu
Allergy and Immunology 58 years experience
Unusual: A normal CRP suggests that there is no significant inflammation going on. The SED rate can be elevated when there is anemia or estrogen treatment even without inflammation. In general, I prefer CRP. As for pleuritis, it is a clinical diagnosis and not diagnosed by a lab test. There may be other explanations for this discrepancy but the above is what I can think of.
Last updated Aug 12, 2015

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