Cortisol effect: Cortisol present in the blood undergoes diurnal variation; the level peaks in the early morning (approximately 8 a.m.) and reaches its lowest level at about midnight-4 a.m. High glucocorticoid levels simultaneously increase the circulating number of neutrophils (neutrophilia) and decrease the circulating number of lymphocytes (lymphopenia) and monocytes (monocytopenia).
Answered 11/13/2014
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