A member asked:

Which kind of antibody cannot cross the placenta? why not?

A doctor has provided 1 answer
Dr. Al Hegab answered

Specializes in Allergy and Immunology

All except IgG: only IgG can, main reason is size, although IgD and IgE are small too, but mainly not found in the circulation, and function differently, IgG is found in abundance, crosses the placenta during pregnancy to arm the newborn with enough passive immunity during early months of life till capable to produce own antibodies

Answered 6/3/2018

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