A member asked:

What is etoposide (also known as vp16)?

A doctor has provided 1 answer
Dr. Matthew Fero answered

Specializes in Medical Oncology

Chemotherapy drug: Etoposide is a chemotherapy drug based on compounds found in the American Mayapple. It acts by blocking enzymes (topoisomerases) that facilitate the unwinding of DNA - a process needed for DNA replication and cell division. It is toxic to cancer cells, which are characterized by relentless cell division. It is useful in a variety of malignancies ranging from lung cancer to leukemia.

Answered 1/4/2015

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