A 46-year-old member asked:
Where does colorectal cancer affect before metastasis?
1 doctor answer • 1 doctor weighed in
Surgical Oncology 64 years experience
Mesenteric nodes: As colon cancer grows from premalignant cells in the mucosa of bowel it invades the muscularis reaching serosal outer surface (Dukes B). It then invades nodes of the mesentery C1 expanding to 4 or more nodes C2 and then along the mesenteric lymphatics to liver. Subpopulations in the primary however can eventually spread directly to lung or bone depending on their surface antigens.
3.6k viewsAnswered >2 years ago
A 35-year-old member asked:
What ages does colorectal cancer affect?
2 doctor answers • 7 doctors weighed in
Gastroenterology 28 years experience
It varies: Colon cancer can strike from the 20s and beyond, but is much more common in people in their 50s to 70s hence the recommendations to not routinely do colonoscopies in people before the age of 50. Colon cancer that presents before 60 is often genetic whereas after 60 is more likely due to environmental factors like smoking and red meat.
6.2k viewsReviewed >2 years ago
A 36-year-old member asked:
What areas does colorectal cancer usually affect before metastasis?
2 doctor answers • 2 doctors weighed in
Pathology 49 years experience
4.6k viewsAnswered >2 years ago
Last updated Nov 9, 2014
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