A member asked:

How long does mononucleosis fatigue last for adults over 20? are there any ways to ease the symptoms?

7 doctors weighed in across 3 answers

Mononucleosis: It may last months. In some cases, chronic fatigue syndrome is associated with a history of mono. During the acute phase, there is splenic congestion that can lead to rupture with even mild trauma. You should rest, hydrate and eat well, take OTC meds for symptom relief and minimize your contact with others recovered and no longer contagious.

Answered 10/11/2016

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Dr. Deborah Ungerleider answered

Specializes in Pediatrics

Varies: The fatigue from mono is very variable from person to person;unfortunately there is no way to predict how long it will be.If you rest enough and follow your doctor's instructions,it usually lasts 2-3 weeks,but it can be for 2-3 months.Make sure you are getting lots of sleep and not doing physical activities which require a lot of exertion too early. Speak to your doctor if the fatigue is longer.

Answered 8/31/2017

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Mono: Unfortunately it can go on for many months. Rest and hydration are important. Stay in close touch with your doctor

Answered 11/2/2014

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