A member asked:

What is the onset of action of phenergan (promethazine) transdermal gel? how long does it last?

4 doctors weighed in across 2 answers

Phenergan (promethazine) topical: Onset of action of the gel is approximately 20 min, peak in 40 min. Overdose has been reported with gel. Is intended principally for hospital use, or supervised use in SNF setting or Hospice setting.

Answered 10/29/2014

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Dr. Roy Arnold answered

Specializes in Internal Medicine

Depends: On site of application and thickness of skin. Generally transdermal medications have an onset of less than an hour and last up to 6 hours. Thanks for trusting HealthTap!

Answered 10/28/2014

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