Can enfamil cause constipation if given once a day?

Yes: If the baby is used to breast milk than giving a formula bottle once a day can change the bowel pattern. If this is not the question you were asking, please give more details. :)

Formula: It is usually changing from infant formula to whole milk that causes constipation because of the lower sugar content, so no Enfamil does not cause constipation. All the best feeding your little one.