A member asked:

How does acetazolamide work?

3 doctors weighed in across 2 answers
Dr. Mark Reynolds answered

Specializes in Psychiatry

Acetazolamide: As a carbonic andydrase inhibitor, acetazolamide decreases the rate of carbonic acid and hydrogen ion production of the kidney, this increases the excretion of solutes and the rate of urinary output.

Answered 7/19/2013

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Dr. Marybeth Lambe answered

Specializes in Travel Medicine

Makes Blood Acidic: We hyperventilate at altitude, trying to grab more oxygen molecules. We blow off too much CO2 & ruin our acid base balance. We feel unwell. Diamox forces kidneys to excrete bicarbonate, (sodium bicarbonate) a base of carbonic acid; speeding the move toward more normal acid base status--something that would take our bodies days to do. With Diamox, we achieve this much more quickly & avoid minor altitude symptoms.

Answered 3/12/2018

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How many mg of acetazolamide can you take before you overdose?

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