A member asked:

Is there an effective iv antidote for xarelto?

3 doctors weighed in across 2 answers
Dr. Roy Arnold answered

Specializes in Internal Medicine

Activated PCC: Activated Prothrombin complex concentrates are recommended in immediately life threatening situations in which the patient has been taking Factor Xa inhibitors. However, these agents have significant risk and have not been adequately studied. Thanks for trusting HealthTap!

Answered 5/19/2015

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Dr. Milton Alvis, jr answered

Specializes in Preventive Medicine

Yes, ButRarelyNeeded: because, like the other factor Xa inhibitors, the half-life for clearance is short, about 5 -9 hrs for healthy people 20-45 yrs, possibly longer older/sick. Xarelto inhibits clot formation & is Rx'ed because of evidence/concern of forming clots inside blood vessels, not just at blood vessel breaks, thus any bleeding problems are ↑ed. Xarelto does NOT thin blood; blood viscosity does not change.

Answered 5/19/2015

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