Could melanoma or any kind of skin cancer have an effect on your ferritin level?

Yes: Any type of cancer, skin or solid tumor, can cause an inflammatory response. Ferritin is sometimes called an acute phase reactant. It can be elevated in instances of inflammation. It is possible that a inflammatory response in the body due to the presence of cancer could raise the ferritin level. This however, does not mean that every elevated ferritin level is due to cancer!

Not likley: A tumor in the skin is not likely to affect ferritin levels, unless it has spread to the liver.

Possible: If the melanoma has traveled to the GI tract and formed tumors that are bleeding, it would decrease your ferritin levels.