What is androgen insensitivity syndrome in simple words possible for parents?

XY baby is a girl: Without testosterone (t), all babies develop as girls. So a child with 1 x & 1 y chromosome, who would normally be a boy, would develop as a girl if no t was present. In androgen insensitivity syndrome, the t is there, but the cells are insensitive to it, and don't respond, so it's as if the t was not there at all. So an xy genetic boy baby is born looking like a normal healthy baby girl.

On the outside, the: Baby looks like a girl genitally, but lacks all of the inside organs (no uterus or ovaries). The penis is very tiny and occupies the proper position of the clitoris, no scrotum or external testes. The testes do not descend and either underproduce or make no testosterone, and the tissues do not respond to testosterone. Most of these children look and feel like girls, despite the chromosomes x-y=boy.

Keeping It Simple: Androgen insensitivity syndrome (ais) is when a person who is genetically male (who has one x and one y chromosome) is resistant to male hormones (called androgens). As a result, the person has some or all of the physical traits of a woman, but the genetic makeup of a man.