In 1st trimester -- grapefruit seed extract safe during pregnancy?

Yes: Yes this is safe to take but never abuse the product.

Topical use only: German studies of grapefruit seed extract have shown several of these products to be adulterated with benzethonium chloride, a synthetic antimicrobial often used in cosmetics, as well as the preservatives triclosan and methylparaben. http://tinyurl.com/n9xscvh topical use on nail fungus, etc may be okay, but don't use internally.