U.S. doctors online nowAsk doctors free
A 21-year-old member asked:

What are the different stages is the myeloma?

2 doctor answers6 doctors weighed in
Dr. Michael Thompson
Hematology and Oncology 21 years experience
ISS - Greipp et al.: International staging system -- the international staging system (iss) for myeloma was published by the intl myeloma working group in 2005: it is useful for comparing clinical trial , but has limited utility for each individual. Stage i: β2-microglobulin (β2m) < 3.5 mg/l, Albumin >= 3.5 g/dl stage ii: β2m < 3.5 & Albumin < 3.5 ; or β2m 3.5- 5.5 irrespective of serum albumin stage iii: β2m >= 5.5.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Michael Thompson
Hematology and Oncology 21 years experience
Provided original answer
Another staging (older) staging system is: Durie-Salmon staging system (1975) stage I: Hb > 10g/dL normal calcium Skeletal survey: normal or single plasmacytoma or osteoporosis Serum paraprotein level < 5 g/dL if IgG, < 3 g/dL if IgA Urinary light chain excretion < 4 g/24h stage II: fulfilling the criteria of neither I nor III stage III: one or more of Hb < 8.5g/dL high calcium > 12 mg/dL Skeletal survey: 3 or more lytic bone lesions Serum paraprotein > 7g/dL if IgG, > 5 g/dL if IgA Urinary light chain excretion > 12g/24h Stages I, II, and III can be divided into A or B depending on serum creatinine: A: serum creatinine < 2 mg/dL B: serum creatinine > 2 mg/dL
Jul 17, 2011
Dr. Haluk Tezcan
Medical Oncology 36 years experience
Stage I, II and III: There are two staging systems one is iss (international staging system) and salmon-durie staging. Both are a 3 stage system i to iii. In addition to both staging systems there are additional molecular testing that helps with myeloma management. Also there is mgus and smoldering myeloma concepts where observation rather than active treatment is currently recommended.
Created for people with ongoing healthcare needs but benefits everyone.

Related questions

A 48-year-old member asked:
What tests diagnose myeloma?
2 doctor answers4 doctors weighed in
A 30-year-old member asked:
Is plasma cell myeloma hereditary?
2 doctor answers3 doctors weighed in
A 41-year-old member asked:
Wo is at risk for multipule myeloma?
2 doctor answers2 doctors weighed in
A 41-year-old member asked:
What increases my risk for developing myeloma if I tried to avoid sun since 19?
1 doctor answer2 doctors weighed in
A 39-year-old member asked:
Does cytoxin cause myeloma?
1 doctor answer2 doctors weighed in
Last updated Sep 28, 2016
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.