A member asked:

What are the advantages monoclonal antibodies offer over normal antisera?

A doctor has provided 1 answer

More effective: Before Milstein developed the concept of monoclonal antibodies derived from a fused B cell with myeloma cell (hybidoma) all antibodies were polyclonal. They were derived from injecting protein into a horse or cow and extracting the serum which contained antibodies against foreign organisms, and food products. Activity was poor. Monoclonals are now genetically engineered as human and functional

Answered 9/27/2014

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