A member asked:

Hi i 23 years old' i have two kids. i got the depo-provera shot for birth control going on a month, but i'm so moody and irritable. why!

2 doctors weighed in across 2 answers
Dr. Jalal Zuberi answered

Specializes in Pediatrics

Hormonal changes: Deposit shots are notorious for causing mood swings and other mental changes like depression. If this continues, pl consult with your doctor re need to continuation of Depo or switching to other contraception.

Answered 9/23/2014

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Depo is progestin,: and progesterone is the hormone that peaks before one's period is due and is responsible for PMS. Many women get very moody during PMS, and it sounds like you are experiencing some of the same symptoms. Please speak with your doctor about your symptoms if they interfere with normal functioning, definitely before your next dose. Some women benefit from antidepressants for premenstrual mood probl

Answered 9/23/2014

3.7k views

Thank

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Are Depo-Provera shots associated with horrible mood changes?

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