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A 42-year-old female asked:

Dr.said my blood work was fine but globulin was high at4.4(norm 2.0-4.0)a/g ratio was low at .9(norm 1.0-2.4)total protein and albumin normal.this ok?

3 doctor answers4 doctors weighed in
Dr. Carrie Cannon
A Verified Doctoranswered
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Repeat the test.: Your albumin/globulin ratio will be low with a normal albumin and high globulin, since it is simple a ratio of tests. Higher globulin may mean a chronic inflammatory or infectious disease or condition, leukemia or other bone marrow disease, an autoimmune disease such as lupus or rheumatoid arthritis, liver or kidney disease. In your case, the globulin may be elevated due to a past cold or virus.
Dr. Carrie Cannon
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Provided original answer
:)
Sep 16, 2014
Dr. Marvin Ott
Emergency Medicine 20 years experience
Most likely: Lab normal ranges are chosen so that they catch 95% of people's normal. Some people fall outside the norm. Also, there is an inherent error in any test. These values are so close to normal that they probably don't represent any significant issues. Of course, be sure to see your doctor, as they may want to do follow up testing. Hope this helps!
Dr. Philip Miller
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Normal variation: I think these labs are probably more a reflection of normal lab variation, estrogen therapy, diet and nutrition. I truly don't think these labs are consistent with any medical illness; however, they should be repeated in 1 month for comparison and peace of mind.

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Last updated Feb 5, 2020

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