Hi i am 45 usually have cycle every 25-27days. 10 days ago had spotting for a day and a bit now am 6 days late. do not take contraceptives. ?

Perimenopause: The most common reason for this in the 40's would be perimenopause. During this phase, menses becomes irregular as the ovaries become less functional. Complete menopause usually occurs in a few years, indicated by absence of menses for a year and usually accompanied by the other symptoms of menopause (hot flashes, etc.). Other medical conditions could also be causing this so talk to your doctor