Could an overdose of diamox (acetazolamide) pills kill you?

Unlikely: Although serious dehydration and salt depletion has occurred requiring hospitalization and supportive care, overdose of Diamox (acetazolamide) is very survivable. The half life of Diamox (acetazolamide) is 9 hours and is cleared by the kidneys. Usually fluid support is given and often potassium while maintaining the body's in acid base balance. As Diamox (acetazolamide) clears out, the person gradually recovers--usually without any lasting harm.