Can overdosing on clonidine kill you with blood pressure changes?

Possible: Clonidine over dose can cause very low blood pressure and heart rate. If very low blood pressure persists and is not treated in a timely manner it can lead to shock and death.

Clonidine O/D: Clonidine overdose can paradoxically cause elevated blood pressure. Slowed heart rate,drowsiness, weakness, fainting, difficulty breathing, skin that is cool & pale, slurred speech, shivering, constricted pupils, coma, & death can also occur.