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A 20-year-old female asked:

Trying to concieve. mildly high level of androstenedione, testosterone, prg-17-oh and dhea so4. is this serious? taking acth simulation test next week

1 doctor answer1 doctor weighed in
Dr. Thomas Knecht
A Verified Doctoranswered
33 years experience
CAH: Hi. It sounds like you may have a condition called non-classical congenital adrenal hyperplasia (CAH) due to a sluggish enzyme activity (21-hydroxylase). This can interfere with periods and fertility, and can cause hirsutism. Any of those things going on? The ACTH stim test can tell if 17(OH)progesterone and androtenedione go up out of proportion to the rise in cortisol. Good luck!
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Last updated Nov 3, 2016


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