A member asked:

Does zoloft (sertraline) cause stomach pains? i've been experiencing bad stomach pains after the second day taking it. is it a coincidence?

2 doctors weighed in across 2 answers
Dr. Robert Grindstaff answered

Specializes in Addiction Medicine

Zoloft (sertraline): Yes it can Zoloft (sertraline) is an SSRI and works on the serotonin receptors in the brain. The gut also has serotonin receptors which may cause some discomfort or cramping. If this is the case it should resolve in a few days

Answered 9/2/2014

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Serotonin receptors: Gastrointestinal side effects are common with the SSRI's, i.e Zoloft, Paxil, (paroxetine) Prozac, etc, because, like the brain, the gastrointestinal tract also is loaded with serotinin receptors. You should see whoever prescribed this for you and discuss alternatives.

Answered 3/29/2018

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