U.S. doctors online nowAsk doctors free
A 40-year-old member asked:

Does fabry disease affect only males?

2 doctor answers4 doctors weighed in
Dr. Mohammad Homsi
Neurology 33 years experience
Fabry disease: Fabry disease is a hereditary disease and transmitted as x-linked recessive, meaning that the carrier mother transmits the disease to 50% of her sons, in some cases females can be affected by inactivation of the other x chromosome in female patient who usually has xx, in that cases the disease may be mild comparing to severe one in the male patient.
Dr. Rodeen Rahbar
Vascular Surgery 20 years experience
Not always: The mutation is carried on the x-chromosone. Men have one y and one x chromosome, therefore they tend to express the gene product. Women have two x chromosomes, so it depends on which x chromosome becomes more active. In some unlucky women, they can express the full blown symptoms of fabry's disease. There are also some special cases of xy women out there, they would be likely to have symptoms.

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Free
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership

Related questions

A 47-year-old member asked:
2 doctor answers3 doctors weighed in
A 35-year-old member asked:
1 doctor answer4 doctors weighed in
A 32-year-old member asked:
1 doctor answer3 doctors weighed in
A 23-year-old member asked:
2 doctor answers6 doctors weighed in
A 41-year-old member asked:
2 doctor answers7 doctors weighed in

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Free
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership
Last updated Oct 3, 2016

People also asked

Related topics

Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.