A 29-year-old member asked:
Why do ace inhibitors cause hyperkalemia?
1 doctor answer • 4 doctors weighed in

Dr. Rajesh Boorguanswered
Nephrology and Dialysis 28 years experience
Block aldosterone: The primary mechanism of action of a ace inhibitors is to interrupt the renin angiotensin system. One of the results is reduced aldosterone synthesis. Aldosterone is an important hormone responsible for regulating potassium excretion by the kidney. Thus blocking aldosterone reduces the capacity of the kidney to excrete potassium.
5.9k viewsReviewed >2 years ago
Last updated Dec 10, 2019
People also asked
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership
Disclaimer:
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.