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A 29-year-old member asked:

why do ace inhibitors cause hyperkalemia?

1 doctor answer4 doctors weighed in
Dr. Rajesh Boorgu
Nephrology and Dialysis 27 years experience
Block aldosterone: The primary mechanism of action of a ace inhibitors is to interrupt the renin angiotensin system. One of the results is reduced aldosterone synthesis. Aldosterone is an important hormone responsible for regulating potassium excretion by the kidney. Thus blocking aldosterone reduces the capacity of the kidney to excrete potassium.

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A 41-year-old member asked:

Can I use an ACE wrap to ease fibromyalgia and/or raynaud's?

2 doctor answers9 doctors weighed in
Dr. Wm. Marcus Spurlock
Preventive Medicine 40 years experience
Muscle Pain: Ace wraps do not usually relieve the pain from either fibromyalgia or raynaud's. Raynaud's benefits from heat. Fibromyalgia requires a comprehensive program to help with the pain syndrome.
A 39-year-old member asked:

What sort of blood pressure problem requires the use of an ACE inhibitor?

2 doctor answers10 doctors weighed in
Dr. Irv Loh
Dr. Irv Lohanswered
Cardiology 49 years experience
Any, if tolerated: Ace inhibitors are a cornerstone of almost any hypertensive patient, especially if a patient has diabetes or heart failure. Monitoring of kidney tests and potassium and watching for cough or rarely rashes or swelling of the lips and eyelids are adverse effects that need medical attention.
A 31-year-old member asked:

Explain ACE inhibitor use as a anti hypertensive?

2 doctor answers4 doctors weighed in
Dr. Robert Vogt Lowell
Specializes in Pediatric Cardiology
Relaxes vasc muscle: Angiotensin i is a hormone that is converted to angiotensin ii with the help of the angiotensin converting enzyme (ace). Angiotensin ii is a very powerful constrictor of vascular muscle and in doing so increases the pressure inside the vessels (the blood pressure). If you inhibit (or neutralize) the ace then you don't produce as much angiotensin ii and the BP does not increase.
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A 82-year-old member asked:

Why might an arb be more effective in stabilizing blood pressure than an ACE inhibitor?

2 doctor answers9 doctors weighed in
Dr. Harris Cohen
Family Medicine 21 years experience
ARB vs. ACE: Different people respond to blood pressure medications differently -- so in some people, an arb may be more potent than an ace, and in others vice versa. These medications work at different parts of the renin-angiotensin pathway.
A 40-year-old member asked:

How do ACE inhibitors reverse microalbuminuria?

1 doctor answer1 doctor weighed in
Dr. Bennett Werner
Cardiology 44 years experience
Unclear: I don't believe that the mechanism is well understood but they do act on the renal glomerulus, improving membrane integrity, reducing protein leakage, and thus do help microalbumenuria. In addition, they also lower blood pressure which is also beneficial.

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Last updated Dec 10, 2019

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