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A member asked:
What happens if heparin affects the formation of thrombin then why pt is not prolonged?
A doctor has provided 1 answer
Two pathway measures: The PT can be with VERY HIGH doses of heparin but generally remember our coagulation system has two primary enzymatic pathways measured differently in the lab 1. Intrinsic system :measured by aPTT (activatted partial thromboplastin time) and prolonged by heparin and 2. Extrinsic system: measured by PT (prothrombin time) and prolonged by coumadin (warfarin).They then converge at the final common pathway.
Answered 8/3/2014
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