A member asked:

Are irreversible damages caused by taking nicotinic acid (more than 1000 mg per day) for years? or if the intake is blocked, is the damage eliminated?

A doctor has provided 1 answer

Likely reversible.: Many have taken niacin at doses greater than 1000 mg per day, and inflammation of the liver, muscle aches, rise in blood sugar, gout attacks are usually totally reversible once the medication is discontinued. The body is a remarkable thing, very good at healing itself once insults are removed. Take heart!

Answered 5/11/2015

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Where are the muscarinic and nicotinic receptors?

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