A member asked:

Are 3-methylhistidin in serum and 1-methylhistidine in urine metabolites of histamine? thank you.

A doctor has provided 1 answer

Histamine: N-methylhistamine and N-methylimidazole acetic acid are specific metabolites of histamine, while imidazole acetic acid is not. Levels of N-methylhistamine or N-methylimidazole acetic acid, which can be measured in plasma or urine, may also reflect overall levels of released histamine for several hours(6-8) after allergic/ anaphylactic reaction. Hope this info helps

Answered 7/21/2014

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