Could supllement nettle root cause side effects on brain ( if it is used for a long time)?and is it possible to associate it with minoxidil 5%?

Probably not: Probably not the cause of your mental condition. OK to use at same time as topical minoxidil. Known as a TNF inhibitor and used for prostate enlargement, though the real world effects are mostly placebo. Save your money and discard the nettle root. See a physician for your mental changes. Do you sleep well? Are you depressed? Are you worried?