A member asked:

How would abnormal lipid metabolism leads to plaque formation in atherosclerosis?

4 doctors weighed in across 2 answers
Dr. David Krulak answered

Specializes in Family Medicine

Atherosclerosis: Textbook chapters are devoted to this, and we have only 400 characters. Short version is that abnormal metabolism increases bad cholesterol. This cholesterol accumulates with smooth muscle and macrophages under the surface lining of an artery, creating a plaque that pushes into the vessel and reduces blood flow.

Answered 7/7/2014

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High levels: Of circulating lipids like hypertrigliceridemia /hypercholesterolemia may results from abnl metabolism and they are the perfect setup for plaque formation by damaging the inner layer of the arteries, by build up in the arteries and eventually plaque formation. Common locations and common symptoms result from deposition in coronary arteries resulting in MI, carotid arteries resulting in stroke etc

Answered 8/10/2019

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Related Questions

A member asked:

What is the difference between atherosclerosis, high cholesterol and plaque ?

7 doctors weighed in across 2 answers