Unlikely: Claritin (loratadine) is considered a non-sedating antihistamine. By package insert it is associated with 7% sedation. Higher doses and taking medication that slows the metabolism of loratadine such as erythromycin, cimetidine (Tagamet) or ketoconazole can cause sedation even with 1 tablet. Rarely, it is an upper, but this is unusual.
Answered 7/7/2014
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