A member asked:

Does marijuana interact with zoloft (sertraline)? if so, what happens?

A doctor has provided 1 answer
Dr. Amanda Itzkoff answered

Specializes in Psychiatry

MJ & Zoloft (sertraline) ?: There is no technical interaction between these two. In some states, it is legal to prescribe marijuana for treatment of anxiety. However, marijuana can also exacerbate anxiety & depression. I note you also mention that you suffer from breathing problems. Smoking marijuana may be doing you more harm than good. Talk with your doc about your use, and get recommendations abt what's best 4 u. Be well!

Answered 11/5/2016

3.9k views

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