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A member asked:

I am complement deficient without an autoimmune disorder. what is making me sick?

A doctor has provided 1 answer
Dr. John Chiu answered

See rheumatologist: Something is eating up your complement and you may need a very good rheumatologist to find why whether there is an autoimmune process going on since negative ANA and RF do not rule out all autoimmune processes. If no cause can be found by your local MD, consider going to an university center.

Answered 6/17/2014

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