A 34-year-old female asked:
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what could cause low mcv and high rdw but normal mch, hemoglobin, and hematocrit for over a year?

1 doctor answer
Dr. Ed Friedlander
44 years experience Pathology
How low?: Reference ranges are set so that several percent of healthy folks fall outside on either end. If your peripheral smear is unremarkable and the MCV above 70, I'd forget the whole thing. My RDW is always high from donating blood. There are some variants of thalassemia minor that will produce this and puzzle people over a lifetime, though MCH is usually lowish.
Answered on Aug 24, 2018
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