A member asked:

What causes retinoblastoma?

5 doctors weighed in across 2 answers

RB gene mutation: Inherited or acquired loss of both copies of the retinoblastoma gene leads to uncontrolled proliferation of cells and can cause many cancers, including retinoblastoma.

Answered 2/1/2012

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Retinoblastoma: Some cases are inherited and some cases are the result of spontaneous mutations of the retinoblastoma gene.

Answered 12/15/2012

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