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A 36-year-old member asked:

what is strength of roxanol (morphine) compared to hydrocodone?

4 doctor answers4 doctors weighed in
Dr. Einar Ottestad
Pain Management 19 years experience
Morphine: Roxanol is a brand of morphine. It is generally thought to be as potent as morphine or just a bit stronger.
Dr. David Rosenfeld
Pain Management 27 years experience
Less potent: Roxanol is a brand of morphine. Roxanol is less potent than hydrocodone by a factor of 30 to 20 (30 mg of morphine is equal to 20 mg of hydrocodone).
Dr. Thomas Namey
Rheumatology 48 years experience
Only orally, since 20-24% of oral morphine sulfate is absorbed. I think this an important distinction, since hospital use of morphine is\ parenteral.
May 12, 2012
Dr. David Rosenfeld
Pain Management 27 years experience
Less potent: Morphine is less potent than hydrocodone by a factor of 2:3 (20 mg of hydrocodone is equal to 30 mg of morphine).
Dr. David Rosenfeld
Pain Management 27 years experience
Less potent : Both are good medications. Hydrocodone is more potent than morphine by a factor of 2:3.

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A 40-year-old member asked:

Is it safe to take hydrocodone to reduce the pain and tenderness of mono?

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Dr. Ron Jones
Family Medicine 45 years experience
Yes: Yes it will. However, take sparingly as most hydrocodone preparations are combined with Acetaminophen which can "stress" the liver. Liver inflammation is present in mononucleosis.
A 44-year-old member asked:

Is it safe for me to eat grapefruits while i'm taking sertraline and hydrocodone?

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No: Grapefruit can affect the breakdown of sertaline (zoloft) and could make it ineffective.
A 29-year-old member asked:

Will they give you enough morphine if you are at the end to keep you pain free?

1 doctor answer8 doctors weighed in
Dr. Alvin Lin
Geriatrics 30 years experience
Yes!: I'm sorry that you have to ask that question, but yes, we should. If you're worried, ask for consult from hospice & palliative care specialist. Better yet, ask to see if you qualify for hospice benefits. If you do, we can then focus on caring for you (and your family) rather than on curing you when a cure isn't realistic.
A 34-year-old member asked:

How does the strength of roxanol (morphine) compare to hydrocodone?

1 doctor answer1 doctor weighed in
Dr. William Newton
Pain Management 19 years experience
Depends: Roxanol is morphine. Hydrocodone and morphine are essentially the same when comparing strengths. Everyone responds differently to opioids therefore one may feel stronger or have more side effects than the other.
A 34-year-old member asked:

Please help! what is the strength of roxanol (morphine) compared to hydrocodone?

1 doctor answer1 doctor weighed in
Dr. Alan Wartenberg
A Verified Doctoranswered
A US doctor answeredLearn more
No easy answer: Even in the modern immediate-release forms, morphine is poorly absorbed in many people, broken down by stomach acid/enzymes and taken out in "first pass" through the liver. Conventional wisdom is 5 mg of hydrocodone is equivalent to 7.5 mg of morphine orally, and 2.5 mg of morphine if given by injection. There is a lot of individual variation, and equivalency tables are often wrong and dangerous.

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Last updated Feb 1, 2015

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