A member asked:

I'm currently taking 40 mgs cymbalta (duloxetine) for nerve pain, can i take 10 mg of prednisone with that.for breaktrough pain, can i take 5mg oxycodone.

4 doctors weighed in across 2 answers
Dr. Robert McMurtrie answered

Specializes in Pain Management

Talk to your doctor: Generally Prednisone isn't used as needed. It is usually prescribed in a tapering dose to decrease inflammation. There are no significant interactions found with the combination of cymbalta, (duloxetine) Prednisone and oxycodone. Your doctor would rather know how you are feeling to make changes if needed rather than have you make changes on your own.

Answered 8/2/2014

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Dr. David Mcadams answered

Specializes in Internal Medicine

Yes, but: You can take Cymbalta (duloxetine) and Prednisone together. You can also take oxy for breakthrough pain. The only caution I have is that taking Prednisone without a clear diagnosis behind your pain might not be the best option due to the side effect profile of prolnged Prednisone use.

Answered 11/28/2017

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