Can too much anti-malaria drug cause miscarriage?

Yes,: A pregnant shouldn't as a general rule take no medication, illicit or not during pregnancy, especially during the first trimester. One glass of wine with dinner not a problem. If there is a compelling need to use a drug, the benefit vs the risk must be weighed by a specialist (high-risk obstetrician). If your planning travelling to an endemic malaria part of the world---fagetaboutit, seriously!