Can you tell me how prozac, (fluoxetine) curare, ectasy, nicotine and alcohol affect how neurotransmitters pass synapes?

Really can't: None of them actually change what happens at synapses except curare, which blocks acetylcholine from being released in muscles and causes paralysis. Nicotine acts at nicotinic cholinergic neurons to increase numbers of synapses, resulting in muscle relaxation and mild stimulation. Ecstacy increases Dopamine in pleasure centers. Alcohol indirectly effects Dopamine as well, and also NMDA receptors.