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A member asked:

Can you tell me how is it possible that buprenorphine and butorphanol are partial agonists-antagonists?

A doctor has provided 1 answer
Dr. Romanth Waghmarae answered

Specializes in Pain Management

Agonist/antagonist: They are agonists at some receptor types and antagonist at other receptor types. Also agonist/antagonist effects may also be dose dependent as well.

Answered 6/28/2014

3.9k views

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