A 37-year-old member asked:
Can you tell me why there are often life-threatening aortic defects associated with marfan's syndrome?
2 doctor answers • 2 doctors weighed in

Dr. Bennett Werneranswered
Cardiology 46 years experience
Yes: Aortic dissection is a known complication.
Created for people with ongoing healthcare needs but benefits everyone.
4.1k viewsAnswered >2 years ago

Dr. Matthew Ostromanswered
A US doctor answeredLearn more
Firbrillin 1: In short, problem in Marfan's is a misfolding of a protein involved in the structure of connective tissue in various parts of the human body, notably in tissues such as mitral and aortic valves and aorta, which can lead to mitral valve prolapse, aortic dilation and aneurysms, aortic regurgitation, aortic dissection, etc along with extra cardiac manifestations.
Created for people with ongoing healthcare needs but benefits everyone.
4.1k viewsAnswered >2 years agoMerged
Last updated May 19, 2014
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