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A 16-year-old male asked:

About to increase my zoloft (sertraline) dose from 50mg to 75mg. will the sexual side effects get worse or stay the same usually?

1 doctor answer2 doctors weighed in
Dr. Neil Liebowitz
Psychiatry 40 years experience
Not much difference: Sexual side effects on SSRIs are generally dose related, but going from 50-75mg of Zoloft (sertraline) is not big enough to make much difference. If depression/anxiety improve sexual function might improve esp interest. Young men often find it helps sexual function as it prevents premature ejaculation . When I have a young man be very sensitive to sexual side effects of SSRIs, I suspect bipolar disorder.
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Last updated May 8, 2016


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