Can you tell me if atorvastin causes puffy ankles?

I think potentially: Any medication can. If you noticed this happen after taking the medication, you can always under your docs guidance stop the medication and see if the ankle swelling stops. He other thing to consider is are you using brand or generic. Not, all medicines are the same even when the name is the same. Another words Lipitor (atorvastatin) and a generic version may not be identical.