I tend to get this empty feeling inside my chest, a sense of loneliness, helplessness and isolation. what does this sound like?

Sounds like you : are depressed and could benefit from speaking with a psychologist about how you are feeling.

Eval: Provided there is nothing physically wrong with you, get a full evaluation from a psychiatrist to assess for whatever bothers you and consider medication. Also get a referral to a reputable psychotherapist who specializes in whatever your diagnosis happens to be.