A member asked:

How exactly does sofosbuvir and ribavirin work to kill the hcv virus?

A doctor has provided 1 answer
Dr. Charles Cattano answered

Specializes in Gastroenterology

Sovaldi + ribavirin: Sovaldi (sofosbuvir) is a uridine nucleotide analog prodrug that is converted in liver to an active metabolite that inhibits the hcv ns5b rna-dependent RNA polymerase, which is essential for viral replication. The combination is fda-approved, forms an aasld/idsa recommended treatment arm for multiple genotypes, as well as for hcv/hiv coinfected patients, ; those with liver cancer pre-transplant.

Answered 6/10/2014

4.2k views

Thank

Related Questions

A member asked:

Will heat kill the hepatitis C virus?

A doctor has provided 1 answer

A member asked:

Could soap and water kill the hepatitis C virus?

A doctor has provided 1 answer

A member asked:

Can Hepatitis C live in urine or would urine kill the virus?

A doctor has provided 1 answer

Online Primary Care Doctors Accepting New Patients

$44 video appointments available today with a membership as low as $15/month

Book a Video Appointment
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question