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A member asked:
What's sister's riskof colon cancer if parent had it + she has1 snp from that parent + 2 snps from other parent associated with it? 23&me risk is 4.8%
2 doctors weighed in across 2 answers
Not sure...: ...I get your whole question, especially the 4.8% part. If you have significant family history (which seems to be the case), i advise you talk to a specialist with expertise in genetics and risk assessment. He/she will get a full pedigree and obtain additional personal info to help determine your risk and what to do to reduce it. You are young but don't put it off.
Answered 4/14/2014
4.2k views
Need more info: Need a detailed family history. Multiple colon cancers in family increases the risk of colon cancer for other family member by 2-4 fold. If high risk familial syndrome (fap, hnpcc) is demonstrated, the life time risk would be as high as 90-100%.
Answered 12/11/2016
4.2k views
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