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A 21-year-old member asked:

What are the side effects of bone marrow transplantation tor thalassemia?

2 doctor answers5 doctors weighed in
Dr. Robert Kwok
Pediatrics 34 years experience
Many possible: Possible side effects from a bone marrow transplant include: rejection of the donor marrow, graft vs. Host disease (donor cells attack the recipient), infections (bacterial, viral, fungal, etc...), mouth sores, stomach ulcers, diarrhea, liver disease, seizures, nerve pain, lung inflammation, hormonal deficiencies, osteoporosis, future cancers, etc...
Dr. Brant Ward
Allergy and Immunology 14 years experience
Many risks: Chemotherapy is often used to prepare your bone marrow to receive the transplant and can have many side effects. You will be at increased risk of infection until the new bone marrow "takes hold". Immune cells in the transplant can also attempt to "reject" your body, called graft vs host disease. For certain diseases, the benefits outweight the risks. Be sure to discuss this with your hematologist.

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A 21-year-old member asked:

What is the success rate of bone marrow transplantation for thalassemia?

2 doctor answers6 doctors weighed in
Dr. Robert Kwok
Pediatrics 34 years experience
Depends: The bone marrow transplant team at each transplant center can give details of how many of their transplants "take" and how many are "rejected" after transplantation. The numbers may be different for stem cells from umbilical cord blood compared to stem cells from donor bone marrow. The better the match between donor and patient, the less likely a rejection will occur.
A 22-year-old member asked:

What is the cost of bone marrow transplantation for thalassemia?

2 doctor answers5 doctors weighed in
Dr. Robert Kwok
Pediatrics 34 years experience
Not sure: Cost vary for bone marrow transplantation, depending on the number of hospital days, number of ICU (intensive care unit) days, complications, rejection events, infections, etc... The bone marrow transplant team at each transplant center can give details of costs. A rough estimate would be a quarter million dollars or more.

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Last updated Sep 16, 2013
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