What is the survival rate with melanoma in situ stage 1?

Melanoma: Depends on how wide the excision was done. Usually over 90% over 10 years.

Nearly 100% cure: If the area is removed in its entirety, most patients have essentially a 100% cure rate. The catch is that anybody who has 1 melanoma is at risk for developing other melanomas at other skin sites for the rest of their life. So even though the in situ melanoma site is essentially cured, you still have to avoid sun exposure and keep up with your skin screenings on an annual basis!