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A 35-year-old member asked:

what is the etiology of ewing sarcoma?

2 doctor answers4 doctors weighed in
Dr. Ahmad M Hadied
Orthopedic Surgery 49 years experience
No body know: For sure what the etiology a lot research are going on.
Dr. Noah Federman
Pediatric Hematology and Oncology 19 years experience
The underlying molecular defect in Ewing sarcoma is a translocation of two genes creating a fusion product. The most common product is EWS-FLI1. This is present in about 90% of Ewing sarcomas. The fusion protein is believed to be the inciting cancer event believed play a role in abnormal transcription, translation and the overall malignant phenotype of Ewing sarcoma.
Jan 21, 2013
Dr. Noah Federman
Pediatric Hematology and Oncology 19 years experience
Etiology ewings: The underlying molecular defect in ewing sarcoma is a translocation of two genes creating a fusion product. The most common product is ews-fli1. This is present in about 90% of ewing sarcomas. The fusion protein is believed to be the inciting cancer event believed play a role in abnormal transcription, translation and the overall malignant phenotype of ewing sarcoma.

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A 39-year-old member asked:

Does kaposi sarcoma develop over time or do marks appear all at once?

2 doctor answers10 doctors weighed in
Dr. Morris Westfried
Dermatology 46 years experience
Over time: Lesion develop slowly over months and continue to develop over a period of years.
CA
A 35-year-old member asked:

What are the stages of a kaposi sarcoma?

2 doctor answers8 doctors weighed in
Dr. Morris Westfried
Dermatology 46 years experience
Skin only, nodes ,: Lapland in elderly involvesxskin only using on the feet, can spread to lymph nodes and nil ate stages internally to liver and spoken as well as esophagus and lung. Early kpaosi is easily treatable.
A 48-year-old member asked:

What is the difference between carcinoma and sarcoma?

3 doctor answers5 doctors weighed in
Dr. Edward Gold
Internal Medicine 44 years experience
One in the same: Carcinoma is a general term for cancer. Sarcoma is a type of carcinoma that develops from connective tissue.
A 32-year-old member asked:

What kind of doctor treats kaposi sarcoma?

2 doctor answers4 doctors weighed in
Dr. Michael Thompson
Hematology and Oncology 20 years experience
Derm, Onc, HIV: Ks may be treated by a variety of types of physicians including: dermatologist hiv specialist hematologist/oncologist.
A 41-year-old member asked:

What are the different stages of kaposi sarcoma?

1 doctor answer1 doctor weighed in
Dr. Joel Gallant
Infectious Disease 36 years experience
Skin vs. visceral: There are no specific stages, but the earliest form of ks is usually cutaneous (skin lesions), which can be mild or severe depending on how extensive it is. People with extensive ks or more advanced immunosuppression can develop visceral ks: involvement of internal organs such as the GI tract or lungs. Of those, lung involvement is usually has the worst prognosis.

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Last updated May 16, 2013

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