A member asked:

What is the etiology of ewing sarcoma?

5 doctors weighed in across 2 answers
Dr. Ahmad M Hadied answered

Specializes in Orthopedic Surgery

No body know: For sure what the etiology a lot research are going on.

Answered 1/1/2023

5.9k views

Thank
Dr. Noah Federman answered

Specializes in

Etiology ewings: The underlying molecular defect in ewing sarcoma is a translocation of two genes creating a fusion product. The most common product is ews-fli1. This is present in about 90% of ewing sarcomas. The fusion protein is believed to be the inciting cancer event believed play a role in abnormal transcription, translation and the overall malignant phenotype of ewing sarcoma.

Answered 1/21/2013

5.4k views

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