Need help docs! my 77 year old grandmother is having severe constipation , even anema hasn't worked. need urgent advice!?

Seek attention: If your grandmother has not had a BM for more than 7 days dispite using laxatives, suppositories, and enemas as directed she is likely also having abdominal pain, maybe even decreased appitite and nausea/vomiting. She may have obstipation. This means the stool is stuck inside. Medication, decreased oral fluids can cause. If all these treatments were tried w/no help needs exam.