I read on the medication guide: accutane absorption is enhanced when given with high fat meal. some doctors advise low-fat diet. what's the point?

Choose your issue: The medication is not as well absorbed as it passes through your gut unless fat is in the mix. Without it, some of the medication passes through your system and ends up in your poo. If you would rather follow the "low-fat" mantra for its questionable health benefits you choose to lose some of the med. The choice is yours. A bit of fat intake as you take your med is not such a negative overall.